One Tox 100

One Tox 100 – Korean Botulinum Toxin Type A for Safe and Effective Aesthetic & Therapeutic Use

1. Overview & Manufacturer
One Tox 100 is a botulinum toxin type A product developed and manufactured in South Korea, designed for non-surgical facial aesthetics and emerging therapeutic indications. Although a newer name on the global market, One Tox is produced under GMP-compliant pharmaceutical standards and offers a cost-effective, high-purity neurotoxin option for clinics and medical professionals.

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2. Composition & Packaging

• Each vial contains 100 units of Clostridium botulinum toxin type A, in lyophilized (freeze-dried) powder form

• Requires reconstitution with 0.9% sterile saline (NaCl) prior to injection

• Designed with low protein content, minimizing the risk of antibody development and ensuring long-term treatment success

• Developed using modern purification and manufacturing techniques to ensure potency and safety

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3. Mechanism of Action
One Tox works by inhibiting the release of acetylcholine at the neuromuscular junction. This temporary blockage results in:

• Relaxation of overactive or expressive facial muscles

• Reduction of dynamic wrinkles

• Control of muscle-related conditions and excessive sweating (hyperhidrosis)

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4. Key Advantages

• ✅ Fast onset of action: Visible results typically begin within 2–4 days

• ⏳ Long-lasting effect: Effects generally last 3–6 months, depending on the area and dose

• 🎯 Smooth, controlled diffusion: Helps achieve natural-looking, symmetrical outcomes

• 💉 High purity formulation: Reduces immunogenicity and supports repeat usage

• 💰 Cost-effective: An excellent alternative to premium brands, especially for high-volume clinics

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5. Clinical Applications

Aesthetic Treatments:

• Glabellar lines (frown lines)

• Forehead wrinkles

• Crow’s feet

• Bunny lines (nasal wrinkles)

• Chin dimpling and lip lines

• Masseter muscle reduction (jaw slimming)

• Platysmal bands (neck lift)

Therapeutic (Off-label) Uses:

• Hyperhidrosis (underarms, palms, soles)

• Bruxism and TMJ tension

• Facial muscle twitching or spasticity

• Migraine prevention (emerging use)

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6. Suggested Dosage Guidelines (Approximate ranges)

Dosing should be adjusted based on patient anatomy and treatment goals.

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7. Storage & Handling

• Store at 2–8°C (refrigerated); do not freeze

• Protect from light and use reconstituted solution within the timeframe recommended by the manufacturer

• Reconstitute gently with 2.0–2.5 mL saline (yielding 4–5 units per 0.1 mL)

• Administer only by licensed healthcare professionals

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8. Safety & Contraindications
Avoid in:

• Pregnant or breastfeeding patients

• Patients with known allergies to botulinum toxin

• Individuals with neuromuscular disorders (e.g., myasthenia gravis)

• Areas with active infection or skin inflammation

Common side effects may include mild bruising, swelling, or temporary eyelid droop. These are usually self-limiting and resolve without intervention.