Genetoxin 100

Genetoxin 100 – Precision Korean Botulinum Toxin Type A for Safe, Effective Aesthetic & Therapeutic Use

1. Overview & Manufacturer
Genetoxin 100 is a botulinum toxin type A developed by Genetox Co., Ltd., a South Korean pharmaceutical company known for its commitment to producing high-purity, clinical-grade aesthetic injectables.
Genetoxin is formulated for use in both cosmetic wrinkle reduction and therapeutic applications, and is produced in GMP-certified facilities, ensuring international standards of quality, consistency, and safety.

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2. Composition & Presentation

• Each vial contains 100 units of purified Clostridium botulinum toxin type A, in lyophilized (freeze-dried) powder form

• Requires reconstitution with 0.9% sterile saline (NaCl) prior to injection

• Designed with low protein load, which helps reduce the risk of neutralizing antibody formation over repeated treatments

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3. Mechanism of Action
Genetoxin works by blocking the release of acetylcholine at the neuromuscular junction. This results in temporary relaxation of the targeted muscles, which:

• Smooths dynamic wrinkles

• Softens facial expressions

• Reduces muscle hypertrophy (e.g., jawline slimming)

• Helps control excessive sweating (hyperhidrosis)

• Can relieve spasms and tension in select therapeutic cases

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4. Key Advantages

• ✅ High purity, stable potency – ensures predictable clinical outcomes

• ⏱️ Rapid onset – results typically begin to appear within 2 to 4 days

• ⏳ Long-lasting effects – commonly lasts 3 to 6 months, depending on the treatment area and patient response

• 💉 Smooth, controllable diffusion – ideal for both broad areas (forehead) and delicate zones (crow’s feet)

• 💰 Affordable and accessible – a high-quality, cost-effective alternative to premium Western brands

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5. Clinical Applications

Aesthetic Uses:

• Horizontal forehead lines

• Glabellar (frown) lines

• Crow’s feet (periorbital wrinkles)

• Bunny lines (nasal bridge wrinkles)

• Chin dimpling and lip lines

• Masseter muscle reduction (jaw slimming)

• Platysmal bands (neck rejuvenation)

Therapeutic (off-label) Uses:

• Hyperhidrosis (underarms, palms, soles)

• TMJ dysfunction and bruxism

• Chronic migraine

• Muscle spasticity and localized twitching

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6. Example Dosage Guidelines

Note: Final dosing should be based on patient anatomy and physician assessment.

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7. Storage & Handling

• Store at 2–8°C in the refrigerator; do not freeze

• Reconstitute with 2.0–2.5 mL saline (4–5 U per 0.1 mL)

• Gently roll to mix; do not shake vigorously

• Use within the manufacturer-recommended period after dilution

• Administered only by licensed and trained healthcare professionals

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8. Safety & Contraindications
Avoid use in:

• Patients with neuromuscular disorders (e.g., myasthenia gravis)

• Pregnant or breastfeeding individuals

• Active skin infections at the injection site

• Known allergy to botulinum toxin ingredients

Monitor for typical mild side effects like localized swelling, bruising, or temporary eyelid droop, which are generally self-resolving.